5,6-二氢-3-(4-吗啉基)-1-(4-硝基苯基)-2(1H)-吡啶酮

Product Description:

Product Name: 5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone CAS NO:503615-03-0

Synonyms:

3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one;

Chemical & Physical Properties:

Appearance: white to off-white powder

Assay :≥99.0%

Density:1.357 g/cm3

Boiling Point:506.5℃ at 760 mmHg

Flash Point:260.1℃

5-morpholin-4-yl-1-(4-nitrophenyl)-2,3-dihydropyridin-6-one is used as an intermediate for apixaban.

Apixaban is an oral selective activation factor X inhibitor that can prevent thrombosis, but the adverse effects of bleeding are lower than that of the old drug warfarin. It is used for thrombosis prevention in patients who have undergone hip or knee replacement surgery.

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